Histone H3 (mono methyl K36) Recombinant Rabbit mAb (S-859-505)
SKU: 32261390188

Histone H3 (mono methyl K36) Recombinant Rabbit mAb (S-859-505)

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Description

Histone H3 (mono methyl K36) Recombinant Rabbit mAb (S-859-505)Product Specification Host Rabbit Antigen Histone H3 (mono methyl K36) Synonyms H3K36me Immunogen Synthetic Peptide Location Nucleus Accession P68431 Clone Number S 859 505 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Positive Sample HeLa, MCF7, Jurkat, NIH 3T3, Neuro 2a, mouse liver, PC 12, C6 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid

Product Specification


Host Rabbit
Antigen Histone H3 (mono methyl K36)
Synonyms H3K36me
Immunogen Synthetic Peptide
Location Nucleus
Accession P68431
Clone Number S-859-505
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P, ICC, ICFCM
Reactivity Hu, Ms, Rt
Positive Sample HeLa, MCF7, Jurkat, NIH/3T3, Neuro-2a, mouse liver, PC-12, C6
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000-1:2000 Hu, Ms, Rt
IHC-P 1:5000 Hu, Ms, Rt
ICC 1:500 Hu
ICFCM 1:500 Hu

Background

Histone H3 (mono methyl K36) refers to a variant of histone H3 where the 36th lysine residue (K36) undergoes monomethylation, a crucial epigenetic regulatory mark. This modification is catalyzed by histone methyltransferases (e.g., SETD2, NSD1) and dynamically regulated by demethylases (e.g., KDM2A). H3K36me1 primarily localizes to gene promoters and enhancer regions, where it associates with transcriptional activation. It plays key roles in maintaining chromatin accessibility, facilitating transcriptional elongation, and promoting DNA damage repair. Studies have linked aberrant H3K36me1 distribution to cancers (e.g., leukemia, glioblastoma) and developmental disorders.

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SKU: 32261390188

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4.7 ★★★★★
Based on 130 reviews
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Product Reviews
L
Verified Purchase
Lady B
Los Angeles, US
★★★★★ 5
Best affordable squeaker toy
Color: Crinkle Chicken (Brown), Size: Large, Color: Crinkle Chicken (Brown), Size: Large
my dog is obsessed with this toy, this has became his new comfort toy and after having this for about four months the legs are falling off but it’s very durable. The squeaker also moved from the head of the chicken to the body of the chicken but that’s after it was played with every single day. I love that it has two squeakers and it’s the perfect toy for my dog.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 6, 2026
A
Verified Purchase
Amazon Customer
Massapequa, US
★★★★★ 5
My dogs favorite toy EVER
Color: Crinkle Chicken (Brown), Size: Large
I have a Belgian Malinois who loves any and every toy, but this one is definitely her favorite. She will walk around the house constantly carrying it in her mouth, which is honestly adorable to watch. The squeakers only lasted a couple of months, but I don’t really consider that a downside—I’m kind of grateful they didn’t last forever given how much she plays with it. It still remains one of her most-loved toys even without them. My only word of caution is that if you work from home, this toy makes a lot of crinkling noise. And I mean A LOT. It’s great for keeping the dog entertained, but it can definitely get a little frustrating for humans trying to focus or take calls. Overall, it’s been a big hit in our house and easily one of her favorite toys.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 8, 2026
A
Verified Purchase
Amazon Customer
Draper, US
★★★★★ 5
Super cute
Color: Bunny (Mauve), Size: Small
Super cute and fuzzy. Definitely perfect size for a puppy and not too loud. The fur is very soft and the nose is sown on not a hard piece that can be chewed on. Very good quality too.
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Reviewed in the United States on June 3, 2026
B
Verified Purchase
Buyer
Draper, US
★★★★★ 4
Normally amazing
Color: Spiky Ball (Blue, Orange), Size: Medium
We have purchased these slightly spiky dog balls several times for our very strong jaw heavy chewer dogs and they’ve been amazing. They don’t break down they don’t get torn apart the squeakers don’t even pop out of them. So we ordered another package because we’ve lost a few outside to the lawnmower… oops and the package that got delivered today had only one ball that squeaks and the other does not. THIS IS A PROBLEM ! Unfortunately my female dog got to the new squeaking ball first and my male got to the non-squeaking ball and he was NOT happy. Basically once they claim a ball it’s theirs and the other dogs don’t go near the ball they claimed. So he’s following my female around and every time she squeaks the ball and I’m just waiting for him to attempt to take it from her causing damage to her. Normally… These are amazingly fun, tough, durable but also squeaking balls (that’s rare in a tough ball) that my dogs absolutely love. This time just got a bad batch I guess. When they squeak the dogs LOVE them. After several months of play the squeaker might break inside of the ball but the ball never comes apart or gets damaged. And we as the owners love that they don’t break down are not able to be ripped or torn even by our very strong jawed and big jaw muscle dogs. They are also great for in the house play because they’re small enough that they fit completely inside our dog‘s mouth but obviously not small enough to get swallowed so when we throw them in the house for fetch the dogs can jump up and catch them fully in their mouth so they don’t cause any damage to the walls when they hit the walls. They’re not super heavy but they’re incredibly durable. Definitely worth the price especially if you have heavy chewers or big jaw muscle dogs.
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Reviewed in the United States on April 28, 2026
M
Verified Purchase
MADDY
Omaha, US
★★★★★ 5
Best fun indestructible toy
Color: Crinkle Duck (Yellow), Size: Large
Truly indestructible no matter how much our oittie tries. She has owned it for three months works at destroying every day with no success. She carries it everywhere. Best purchase for chewer, more fun than the popular rubber heavy duty toy. Do not hesitate your pup will thank you for this fun distraction.
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Reviewed in the United States on May 30, 2026

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